State agencies work to improve the health and well being of Colorado's children and youth by coordinating programs at the state level to ensure that those programs are responsive to the needs of communities in order to more effectively serve this population.

Immunization coverage is reported through two measures: in compliance and up to date. In compliance with the Colorado School Immunization Law is defined as being up to date for all required immunizations, having taken a valid exemption, or being in process (having a plan in place with the school to obtain any remaining required immunizations). Up to date is defined as being appropriately immunized for all required immunizations.